Profile: Lauren Richardson
Associate Editor at PLOS Biology
Lauren is an Associate Editor at PLOS Biology. She has a Ph.D in Pharmacology from the University of Washington and did her postdoc at the University of California, Berkeley. Her background is in molecular and cell biology, biochemistry, and genetics.
NoteStreams By Lauren Richardson
Think for a moment, if you will, of all the chemicals that you conscientiously and unconsciously are exposed to everyday. Banal, daily-life things like toothpaste, cosmetics, food additives, pharmaceuticals. They are composed of manufactured chemicals, synthesized and tested in a lab. You have probably never doubted the safety of your toothpaste or the efficacy of your pain reliever, but that comfort and assurance doesn’t come for free. The testing of safety and efficacy of the chemicals that we subject our bodies to depends on the use of animals that may suffer for our conveniences.
Cancer researchers have found that certain types of cancer cells acquire what’s called multidrug resistance by producing lots of antioxidant enzymes and cellular pumps that export drugs out of the cell. This leads to cancers that are much harder to treat, as these cells can inactivate or expel drugs before they are able to perform their cancer-killing actions.